Zaltoprofen

What is a Zaltoprofen?

Zaltoprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used to relieve pain and reduce inflammation. It is commonly prescribed to treat conditions such as arthritis, menstrual cramps, sports injuries, and post-operative pain.

Like other NSAIDs, zaltoprofen works by inhibiting the production of certain chemicals in the body called prostaglandins. Prostaglandins are responsible for pain and inflammation, so by reducing their production, zaltoprofen helps to alleviate these symptoms.

Zaltoprofen is typically taken orally in the form of tablets or capsules, and the dosage prescribed by a healthcare professional will depend on the specific condition being treated. It is important to follow the prescribed dosage and instructions for use, as well as any additional advice given by your healthcare provider.

Description

Zaltoprofen is a nonsteroidal mitigating drug utilized as a pain-relieving, antipyretic, and calming specialist. It also inhibits bradykinin-induced pain responses without affecting bradykinin receptors and is a selective COX-2 inhibitor. In 1993, it was approved for use in Japan.

• Drug Class: NSAID
• Trade names: Soleton
• Molecular Formula – C17H14O3S
• Molecular Weight – 298.4 g/mol
• Generic Name – Zaltoprofen
• Type – Small Molecule
• Groups – Experimental

Synonyms

• Zaltoprofen
• Zaltoprofene
• Zaltoprofeno
• Zaltoprofenum

Zalprofen (January; marketed under the brand name Soleton), an NSAID that acts as an analgesic, antipyretic, and anti-inflammatory agent. In 1993, it was approved for use in Japan. It also inhibits bradykinin-induced pain responses without affecting bradykinin receptors and is a selective COX-2 inhibitor. Zaltoprofen is a natural sub-atomic element.

Information About Zaltoprofen

Patients with lumbar pain, dental pain, osteoarthritis, frozen shoulder, musculoskeletal pain, post-operative pain, cervicobrachial syndrome, and other inflammatory conditions are prescribed zaltoprofen, a non-steroidal anti-inflammatory. This medication has antiphlogistic and analgesic effects. The medication isn’t suggested for patients having dysemia, peptic ulcer, asthma, ulcerative Crohn’s illness, extreme touchiness, and renal or hepatic issues. Zaltoprofen, a special COX-2 inhibitor, specifically hinders Prostaglandin E2 which improves the aggravation pathway. It likewise stops bradykinin-prompted torment without antagonistically influencing the bradykinin receptors.

The dose of Zaltoprofen is usually 80mg threefold day to day before or after dinner. However, the medication may cause gastrointestinal discomfort if taken with food. Take it at the same time each day for the best results. The dose ought not to be expanded suddenly and should be taken at ordinary spans.

The normal symptoms of utilizing Zaltoprofen incorporate regurgitation, heartburn, farting, sickness, stomach torment, blockage, epigastric agony, run, internal organ carcinoma, and others. Taking Zaltoprofen with other medications can either make side effects worse or stop working, so you should talk to a doctor first. Zaltoprofen may interact with sulfonylureas, quinolone antibiotics, and anticoagulants. The amount of salt in the medicine is the basis for this information. The medication may have different effects and employs for different individuals. Counseling an Aggravation The executive’s Expert before utilizing this medicine is fitting.

• Pharmacodynamics – Not Available
• Mechanism of action – Not Available
• Absorption – Not Available
• The volume of distribution – Not Available
• Protein binding – Not Available
• Metabolism – Click on the products listed below to see response partners.

Zaltoprofen

• Zaltoprofen acyl glucuronide
• 10-Hydroxyzaltoprofen
• Zaltoprofen S-oxide
• 10-OH-zaltoprofen
• Zaltoprofen S-oxide

• Route of elimination – Not Available
• Half-life – Not Available
• Clearance – Not Available
• Toxicity – Not Available
• Pathways – Not Available
• Pharmacogenomic Effects/ADRs – Not Available

Borbit (Yoshindo), Peleton (Towa Yakuhin), Peon (Zeria Shinyaku), Salafapinon (Choseido Pharmaceutical), Soleng (Kyorin Rimedio), Soleton (CJ Cheiljedang), Soluirubin (Taiyo Pharmaceutical), and Zaltoprofen (Tatsumi Kagaku, Zatferon, and Zyrogen, all manufactured by Yoo Young) are examples of international and other brands. The accompanying patients might be cautious while utilizing this medication. Make sure to notify your pharmacist and physician.

• In the circumstance that you have recently encountered any unfavorably susceptible responses (tingle, rash, and so on.) to any foods or medicines.
• if you have a peptic ulcer, a blood disorder, a problem with your kidneys or liver, or a problem with your heart.
• if you have asthma or have had asthma in the past.
• if you are breastfeeding or pregnant.
• if you are currently taking any other medications. A few prescriptions might connect to upgrading or reducing restorative impacts. Prescription and over-the-counter medications, as well as dietary supplements, should be avoided.)

 What are the Uses of Zaltoprofen

Fever, osteoarthritis, rheumatoid joint inflammation, ankylosing spondylitis, gout, and relief from discomfort are conditions treated with zaltoprofen. Other advantages include headaches, osteoarthritis, frozen shoulders, body pain – back pain, leg pain, and foot pain.

How does this medication work?

A non-steroidal anti-inflammatory drug (NSAID) is zaltoprofen. It works by preventing the release of certain chemical messengers that cause fever, pain, and inflammation (redness and swelling). This medication’s active ingredient is a non-steroidal anti-inflammatory. It prevents inflammation caused by osteoarthritis, frozen shoulder, and other conditions. It works by selectively inhibiting Prostaglandin E2, an important mediator of the pain pathway.

What are the side effects of Zaltoprofen?

• Gastrointestinal: Loss of craving, queasiness, regurgitating, dry mouth, gastric bothering and clogging, Stomach Agony, Looseness of the bowels, Epigastric Torment, Tooting, Heartburn
• Focal Sensory system: Sleepiness, the sensation of deadness, and unsteadiness
• Skin: Sensitivity to light, such as photosensitivity, itchiness, and rash Low red platelet count and expanded platelet count, Diminished circulatory strain
• Others: fever, respiratory depression, headache, decreased urine output, bleeding gums, fatigue, pain during urination, blood in the urine, an increase in liver enzymes or creatinine level,

What are the other precautions for Zaltoprofen?

In the event of an overdose, the patient should be treated symptomatically for complications like hypotension, a drop in blood pressure, irritation in the gastrointestinal tract, damage to the kidneys, and difficulty breathing. In the event of an overdose, the patient should be treated symptomatically for complications like hypotension, a drop in blood pressure, irritation in the gastrointestinal tract, damage to the kidneys, and difficulty breathing.

Expert Advice For Zaltoprofen

• You have been recommended Zaltoprofen to alleviate agony and irritation.
• Take it with food or milk to stay away from stomach upset.
• Follow your medic’s instructions and take it as demanded. If taken for an extended duration of time, it could cause serious side effects like stomach bleeding and kidney problems.
• Try not to take heartburn cures (acid neutralizers) in the span of two hours of taking Zaltoprofen.
• Abstain from polishing off liquor while accepting Zaltoprofen as it can expand your gamble of stomach issues.
• Inform your medic if you have a history of heart condition or stroke.
• Your PCP may consistently screen your kidney capability, liver capability, and levels of blood parts assuming that you are taking this medication for long-haul treatment.

What are the storage conditions for Zaltoprofen?

• At room temperature, store.
• Safeguard from intensity and dampness.
• Keep out of children’s reach.

What are the interactions of Zaltoprofen?

If you take multiple medications at the same time or combine them with certain foods or beverages, you run the risk of developing a drug interaction. Zydol 50Mg Suspension Drug Interactions Every drug interacts differently with each individual. Before starting any prescription, you ought to counsel your PCP on pretty much all potential communications

Relationship with Alcohol

• Anticoagulants: Zaltoprofen might expand the anticoagulant impacts of medications like warfarin and heparin.
• Quinolones: Convulsions may occur when zaltoprofen and quinolone antibacterials like ciprofloxacin and nalidixic acid are taken together.
• Diabetes mellitus: Combining zaltoprofen with sulfonylurea medications like chlorpropamide, glipizide, and gliclazide may increase the hypoglycemic effects of diabetes medications.
• Sodium: Due to the increased effects of lithium when combined with zaltoprofen, the lithium dose may need to be adjusted.

Description – It is unknown how alcohol affects them. Counseling your primary care physician before consumption is fitting.

Instructions – It is unknown how alcohol affects them. Counseling your primary care physician before consumption is fitting.

Collaboration with Medication – Corticosteroids, Antihypertensives

Disease – Information is lacking, There is no information available regarding food interactions. The data for lab associations cannot be accessed. The possible drug interactions are not all included in the list. Discuss any potential drug interchanges with your medic.

When should Zaltoprofen not be taken? 

(Contraindications)

On the off chance that you are experiencing any of the accompanying illnesses, you shouldn’t accept Zaltoprofen except if your PCP encourages you to do as such – Ulcerative Colitis, Asthma since it could cause an asthmatic assault., Blood anomalies, Cardiovascular infections, and a few cardiovascular passings have been noted for certain NSAIDs.

Allergy

This medication isn’t suggested for use in patients with a known sensitivity to zaltoprofen, other non-steroidal calming prescriptions or some other idle fixings present alongside it. sensitivity to the drug

Severe liver impairment

Due to the increased risk of serious side effects, patients with severe liver impairment should not take this medication.

Severe kidney impairment

This medication isn’t suggested for use in patients with extreme kidney weakness because of the expanded gamble of serious antagonistic impacts.

Key highlights of Zaltoprofen

Is It protected with liquor?

• It is unknown how alcohol affects them. If it is not too much trouble, counsel your primary care medic.

Are there any warnings about pregnancy?

• It is unknown, There are no studies on humans or animals. If it is not too much trouble, counsel your primary care medic.

Are there any breastfeeding admonitions?

• It is unknown, There are no studies on humans or animals. If it is not too much trouble, counsel your primary care medic.

Consumption while nursing?

• This medication is not suggested for use in breastfeeding ladies except if certainly essential. Before taking this medication, you should talk to your doctor about all of the benefits and risks. Your primary care physician might endorse a more secure option in light of your clinical condition.

Is driving while taking this medication safe?

• There is no information accessible. Before taking the medicine, please check with your medic.

Is kidney function affected by this?

• There is no information accessible. Before taking the medicine, please check with your medic.

Is liver function affected by this?

• There is no information accessible. Kindly counsel a specialist before consuming the medication.

Why is Zaltoprofen Prescribed?

Zaltoprofen is a compelling propionic corrosive subordinate (like Ibuprofen atom) NSAID (Non-Steroidal Calming Medication) which is utilized to treat different agony, outer muscle, and joint problems.

A non-steroidal anti-inflammatory drug is zaltoprofen. It is a preferential COX-2 inhibitor that reduces pain and inflammation by inhibiting the production of prostaglandin E2, a biological compound that is physiologically active, at inflammatory sites. Additionally, it prevents pain responses induced by bradykinin, a mediator of pain and inflammation.

Zaltoprofen is endorsed for treating torment and fiery circumstances brought about by different problems like dental agony, outer muscle torment, post-employable torment, lumbar torment, frozen shoulder, osteoarthritis, and cervicobrachial condition.

Dosing schedule (How to take this medicine)

• The dosing schedule that your doctor has given you is (to be written by a healthcare professional): Adults typically take one tablet containing 80 mg of the active ingredient three times a day. Take one to two tablets (80 to 160 mg each) as needed. strictly adhere to the directions.
• On the off chance that you miss a portion, accept the missed portion at the earliest opportunity. Regardless, accepting it is almost time for the accompanying piece, skirt the missed part. Never take two portions simultaneously.
• If you take more than the recommended amount by accident, talk to your doctor or pharmacist.
• Unless instructed otherwise by your doctor, do not stop taking this medication.

Missed Dose

If you miss a quantity of this drug, take it as soon as you remember. Expecting it is almost time for the accompanying piece, skirt the missed part and take the accompanying piece. To compensate for the missed portion, don’t twofold the portion.

Overdose

Look for crisis clinical treatment or contact the specialist in the event of an excess.

Warnings

Warnings for special population

Pregnancy

Pregnant women should not take this drug unless essential. Before taking this medication, you should talk to your doctor about all of the benefits and risks.

Breast-feeding

This medication isn’t suggested for use in breastfeeding ladies except if essential. Before taking this medication, you should talk to your doctor about all of the benefits and risks. Your primary care physician might endorse a more secure option in light of your clinical condition.

General disclaimers

Heart diseases

This medication ought to be involved with alert in patients with heart illnesses because of the expanded gamble of serious unfavorable impacts on the heart. When the medication is used for an extended duration of time, this risk is especially elevated. Depending on the patient’s clinical condition, dose adjustments or replacement with a suitable alternative may be required.

Gastro-intestinal bleeding

After prolonged use, this medication may result in severe gastrointestinal bleeding and perforation. These bad things can happen with or without any warning signs. Patients with a history of gastrointestinal conditions and the elderly are particularly at risk. Depending on the patient’s clinical condition, dose adjustments or replacement with a suitable alternative may be required.

Liver diseases

Due to the increased risk of severe side effects, patients with mild to moderate liver diseases should not take this medication. Some patients may require appropriate dose adjustments. This medication should not be taken if severe liver dysfunction is present.

Kidney diseases

This medication ought to be involved with alert in patients with gentle to-direct kidney illnesses because of the expanded gamble of serious aftereffects. Some patients may require appropriate dose adjustments. This medication should not be taken if severe impairment of kidney function is present.

Other medicines 

Numerous other medications may interact with this one, resulting in severe side effects. As a result, before starting treatment with this medication, it is recommended that you tell your doctor about all of your other medications, including any herbs and supplements.

FAQ

Author: Dr. Prachi Patel